Archives of biochemistry and biophysicsHumansReceptorsG-Protein-CoupledHEK293 CellsChemokines
CXCL17 activates three MAS-related G protein-coupled receptors independently of its conserved C-terminal fragment.
Wen-Feng Hu, Juan-Juan Wang, Jie Yu, Ya-Li Liu, Zeng-Guang Xu, Zhan-Yun Guo
Published: 202610.1016/j.abb.2025.110666
Abstract
C-X-C motif chemokine ligand 17 (CXCL17) is a chemoattractant whose receptor remains controversial. While recent studies identified CXCL17 as an agonist of G protein-coupled receptor 25 (GPR25), it was also reported to activate MAS-related GPR family…
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