Archives of biochemistry and biophysicsHumansOxylipinsMacrophagesTHP-1 CellsLipoxygenase
Lipoxygenase expression and oxylipin analysis in human THP-1 monocyte-derived macrophages.
Abramo Sofia, Mastrogiovanni Mauricio, Rubbo Homero, Gonzalez-Perilli Lucia
Published: 202610.1016/j.abb.2025.110647
Abstract
Macrophages are homeostatic cells with remarkable phenotypic plasticity and key roles in inflammation. Macrophage lipoxygenases (LOX) oxygenate polyunsaturated fatty acids, producing oxylipins that are involved in inflammatory processes. Most insight…
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