Methods in enzymologyHumansRNANucleic Acid ConformationHigh-Throughput Nucleotide SequencingTelomerase
RNA structure analyzed by chemical probing and mutational profiling with sequencing (MaPseq).
Eva Edelson, Nicholas M Forino, Michael D Stone
Published: 202510.1016/bs.mie.2025.10.008
Abstract
RNA chemical probing, coupled with mutational profiling read out by sequencing (MaPseq), is a powerful approach for investigating the folding properties of complex RNA molecules. For over half a century, structure probing methods have advanced our un…
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