Methods in enzymologyHumansRNATransferRNA ProcessingPost-Transcriptional
Preparation of enzymes and libraries for MapID-tRNA-seq to identify chemical modifications in human tRNAs.
Mitchel L Tepe, Weiqi Qiu, Khalil Mimouni, Huiqing Zhou
Published: 202510.1016/bs.mie.2025.10.004
Abstract
Chemical modifications are abundant in tRNAs and play essential roles in tRNA biology and human diseases. We recently reported MapID-tRNA-seq that allows identification of chemical modifications in human tRNAs such as m1A and m3C. MapID-tRNA-seq util…
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