Methods in enzymologyDirected Molecular EvolutionMetagenomicsProtein EngineeringRibosemonophosphatesSubstrate Specificity
Transketolase enzyme discovery and engineering.
Alessia Tonoli, Paul Anthony Dalby, Helen Claire Hailes, Jack William Edward Jeffries
Published: 202510.1016/bs.mie.2025.07.002
Abstract
Transketolases (TKs) are important C-C bond forming enzymes that in vivo transfer a two carbon ketol unit to the acceptors d-ribose-5-phosphate or d-erythrose-4-phosphate. There is significant interest in biocatalytic applications where frequently th…
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