Methods in cell biologyAntibodiesBispecificHumansT-LymphocytesCD3 Complex
Generation and functional evaluation of bispecific T cell engaging antibodies.
Antonio Tapia-Galisteo, Rodrigo Lázaro-Gorines, Luis Álvarez-Vallina
Published: 202510.1016/bs.mcb.2025.02.012
Abstract
T cell engagers (TCE) are a class of bispecific antibodies that simultaneously target a tumor antigen and CD3, acting as a bridge between T cells and tumor cells. They promote the formation of T cell receptor (TCR)-independent canonical immune synaps…
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