Advances in protein chemistry and structural biologyHumansProtein FoldingNeurodegenerative DiseasesProteostasis DeficienciesAnimals
Protein misfolding and neurodegeneration: Mechanisms, implications, and therapeutic strategies.
Asma Shah, Tharini Karthikeyan, Sheema Hashem, Rakesh Kumar, Ajaz A Bhat, Muzafar A Macha
Published: 202510.1016/bs.apcsb.2025.08.012
Abstract
Protein misfolding and aggregation play a pivotal role in the development of neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's disease, and other related disorders. Proper protein folding is essential for cellular function, bu…
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