Advances in protein chemistry and structural biologyAlzheimer DiseaseHumanstau ProteinsPhosphorylationCalpain
The calpain-mediated proteolytic cleavage peptide P10 modulates Tau phosphorylation in Alzheimer's disease.
Subashchandrabose Chinnathambi, Tushar Dubey, Nagaraj Rangappa
Published: 202510.1016/bs.apcsb.2025.08.009
Abstract
Alzheimer's disease is a prominent neurological disorder, which leads to progressive dementia. The microtubule-associated protein Tau is considered one of the major causes of Alzheimer's disease. Hyper-phosphorylation of Tau is considered to be close…
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