Advances in cancer researchHumansDrug ResistanceNeoplasmNeoplasmsRNA-Binding Proteins
AEG-1 on cancer drug resistance: From molecular insights to therapeutic challenges.
Wali Ullah, Hail Kim, Sanghee Han, Minseo Oh, Dong-Chul Kang, Seok-Geun Lee
Published: 202510.1016/bs.acr.2025.06.003
Abstract
Astrocyte elevated gene-1 (AEG-1), also known as metadherin (MTDH), has emerged as a multifunctional oncogene implicated in cancer progression, metastasis, immune evasion, and notably, drug resistance across diverse malignancies. AEG-1 exerts its eff…
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