The Lancet. RheumatologyHumansSclerodermaSystemicRaynaud DiseaseVascular Diseases
Exploiting a unified vascular framework to predict organ-specific complications and accomplish disease modification in systemic sclerosis.
John D Pauling, Yannick Allanore, Maya H Buch, Maurizio Cutolo, Francesco Del Galdo, Christopher P Denton, Stefano Di Donato, Robyn T Domsic, Tracy Frech, Ariane L Herrick, Marco Matucci-Cerinic, Vanessa Smith, Marie-Elise Truchetet, Michael Hughes
Published: 202510.1016/S2665-9913(25)00251-6
Abstract
Immune-mediated vascular endothelial injury is considered one of the earliest pathological features in systemic sclerosis and is thought to occur simultaneously within a broad range of organs, although typically clinically manifesting only as Raynaud…
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