Chinese journal of natural medicinesAlzheimer DiseaseBiological ProductsHumansNeural NetworksComputer
KG-CNNDTI: a knowledge graph-enhanced prediction model for drug-target interactions and application in virtual screening of natural products against Alzheimer's disease.
Chengyuan Yue, Baiyu Chen, Long Chen, Le Xiong, Changda Gong, Ze Wang, Guixia Liu, Weihua Li, Rui Wang, Yun Tang
Published: 202510.1016/S1875-5364(25)60980-0
Abstract
Accurate prediction of drug-target interactions (DTIs) plays a pivotal role in drug discovery, facilitating optimization of lead compounds, drug repurposing and elucidation of drug side effects. However, traditional DTI prediction methods are often l…
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