Chinese journal of natural medicinesExtracellular TrapsAcute Lung InjuryAnimalsSepsisDrugs
Taohe Chengqi decoction inhibits PAD4-mediated neutrophil extracellular traps and mitigates acute lung injury induced by sepsis.
Mengting Xie, Xiaoli Jiang, Weihao Jiang, Lining Yang, Xiaoyu Jue, Yunting Feng, Wei Chen, Shuangwei Zhang, Bin Liu, Zhangbin Tan, Bo Deng, Jingzhi Zhang
Published: 202510.1016/S1875-5364(25)60874-0
Abstract
Acute lung injury (ALI) is a significant complication of sepsis, characterized by high morbidity, mortality, and poor prognosis. Neutrophils, as critical intrinsic immune cells in the lung, play a fundamental role in the development and progression o…
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