The Lancet. NeurologyHumansParkinson DiseaseGastrointestinal MicrobiomeAutoimmunityInflammation
The gut microbiome, systemic inflammation, and autoimmunity in Parkinson's disease.
Matheus de Castro Fonseca, Letizia Zanetti, Stavros Fanourakis, David L Sulzer, Sarkis K Mazmanian
Published: 202610.1016/S1474-4422(25)00382-5
Abstract
Inflammation is a core feature of Parkinson's disease, extending beyond the CNS to include systemic immune activation. The gut microbiome is increasingly recognised as a key regulator of immune function in the gastrointestinal tract, peripheral circu…
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