The Lancet. Infectious diseases
Safety and immunogenicity of a live-attenuated chikungunya virus vaccine in adolescents: final results from a 12-month, double-blind, randomised, placebo-controlled, phase 3 trial in endemic areas of Brazil.
Vera Buerger, Andrea Pfeiffer, Petra Schoengrundner, Jutta Seebacher, Romana Hochreiter, Karin Kosulin, Oliver Zoihsl, Petronela Weisova, Robert Mader, Ana Paula Loch, Eolo Morandi, Mauricio Lacerda Nogueira, Carlos Alexandre Antunes de Brito, Julio Croda, Mauro Martins Teixeira
Published: 202510.1016/S1473-3099(25)00631-0
Abstract
BACKGROUND: Chikungunya outbreaks have recurred in Brazil since 2014. Building on earlier 28-day post-vaccination data, we now report 12-month safety and immunogenicity results of the VLA1553 vaccine in Brazilian adolescents. METHODS: In this double-…
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