Lancet (London, England)HumansFentanylMorphineMethoxyfluraneMiddle Aged
Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial.
Randi Simensen, Lars Olav Fjose, Kjetil Thorsen, Inge Christoffer Olsen, Marius Rehn, Jostein Hagemo, Live Smalberget, Fridtjof Heyerdahl
Published: 202610.1016/S0140-6736(25)01575-2
Abstract
BACKGROUND: Adequate pain control is essential; however, acute pain is often undertreated in prehospital care. This study aimed to evaluate three analgesic regimens for treating acute pain in an ambulance setting. METHODS: PreMeFen is a randomised, o…
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