Therapeutic innovation & regulatory science
In Silico Clinical Trials in Drug Development: A Systematic Review.
Bohua Chen, Lucia Chantal Schneider, Christian Röver, Emmanuelle Comets, Markus Christian Elze, Andrew Hooker, Joanna IntHout, Anne-Sophie Jannot, Daria Julkowska, Yanis Mimouni, Marina Savelieva, Nigel Stallard, Moreno Ursino, Marc Vandemeulebroecke, Sebastian Weber
Published: 202510.1007/s43441-025-00893-w
Abstract
In the context of clinical research, computational models have received increasing attention over the past decades. In this systematic review, we aimed to provide an overview of the role of so-called in silico clinical trials (ISCTs) in medical appli…
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