Clinical drug investigation
Population Pharmacokinetics of Amlodipine and Telmisartan Following Oral Administration of a Single-Pill Fixed-Dose Combination in Healthy Korean Male Subjects.
Eunji Yu, Hee Kyung Hwang, Bo Ram Kim, Hyo Cheol Kim, Seh Hyon Song, Woojin Jung, Christine E Staatz, Min-Soo Kim, In-Hwan Baek
Published: 202510.1007/s40261-025-01513-z
Abstract
BACKGROUND AND OBJECTIVE: Fixed-dose combinations (FDCs) of amlodipine and telmisartan are widely used for hypertension management owing to their efficacy and improved adherence. This study aimed to characterize the pharmacokinetics (PKs) of both dru…
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