Infection
Efficacy and safety of colistin-doxycycline combination therapy in multi-drug resistance Gram-negative infections: a double-blind randomized controlled trial.
Shaghayegh Abaft, Zeinab Yasin, Mahdi Ahmadinia, Azadeh Eshraghi, Behnaz Gholizadeh Niari, Sara Minaeian, Maryam Farasatinasab
Published: 202510.1007/s15010-025-02698-3
Abstract
BACKGROUND & OBJECTIVES: Multidrug-resistant (MDR) Klebsiella pneumoniae poses a critical treatment challenge. Colistin remains a last-resort antibiotic but is limited by nephrotoxicity and resistance. Though clinical data are limited, Doxycycline ha…
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