Drug delivery and translational research
Formulation and evaluation of probucol-LCA nanoparticles for supressing oxidative stress-related retinal degeneration.
Susbin Raj Wagle, Alicia Brunet, Rebekah James, Le Yang Sen, Mikhaela Manuel Lorenzo, Bozica Kovacevic, Mengistie Diress, Thomas Foster, Corina Mihaela Ionescu, Patrick Lim, Livia S Carvalho, Armin Mooranian, Hani Al-Salami
Published: 202510.1007/s13346-025-02010-8
Abstract
Retinal degenerative diseases are a major cause of vision loss worldwide, with oxidative stress being a key pathological driver. This study aimed to develop and evaluate probucol-lithocholic acid (LCA) nanoparticles for targeted retinal protection. N…
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