Drug delivery and translational research
From simulation to application: enhancing preclinical evaluation of dissolvable microarray patches through PBPK modelling.
Maja Railic, Wilhelmus E A de Witte, Stephan Schaller, Sarah Toluwanimi Agboola, Ziad Sartawi, Waleed Faisal, Mohamed Elkhashab, Abina Crean, Sonja Vucen
Published: 202510.1007/s13346-025-01974-x
Abstract
Dissolvable microarray patches (MAP) represent a promising drug delivery platform; however, the absence of standardised protocols for their preclinical evaluation poses a significant barrier to regulatory approval and clinical translation. Physiologi…
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