European journal of drug metabolism and pharmacokinetics
From Interaction to Intervention: Intentional CYP Inhibition as a Scalable Strategy to Expand Access to High-Cost Therapies.
Fernando De la Garza Salazar
Published: 202510.1007/s13318-025-00976-x
Abstract
Intentional cytochrome P450 (CYP) inhibition has been proposed as a pharmacoeconomic strategy capable of reducing oncology drug costs (33-90%) while maintaining clinical efficacy. While the pharmacokinetic effects of CYP inhibition have long been rec…
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