Genes & genomics
Alpha-defensins promote macrophage inflammatory activation via RNF31 signaling.
Jungnam Lee, Naweed Mohammad, Seyoung Mun, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L Brantly, Karina A Serban
Published: 202610.1007/s13258-025-01735-7
Abstract
BACKGROUND: Defensins, small cationic peptides with strong antimicrobial activity, are key effectors of innate immunity. α-defensins, human neutrophil peptides, are produced primarily by neutrophils and serve as an essential component of the airway d…
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