Evaluation of the Concordance of Cancer Diagnostic Probe Findings During Surgery and Suspected Distortion in Pre-surgical Mammography Based on Pathology.

Cancer diagnostic probe stations (CDP) are expensive, and they are better used in patients with suspicious findings in initial mammography. For the first time, this study investigated the compatibility of suspicious findings observed in mammograms of patients before surgery with CDP findings based on pathology findings as the gold standard. This prospective study was conducted on 26 patients with breast cancer candidates for conservative surgery with suspicious findings in the initial mammography, who were referred to our institute between April 2024 and September 2024. Ultrasound and mammography findings before surgery, frozen findings, CDP during surgery, and pathology results of patients were collected using a checklist. A breast fellowship and a radiologist, with the guidance of the positions and hourly codes of the Quadrants of Breasts, classified the position of suspicious findings in CDP and mammography. The concordance rate between the two methods was evaluated with the Kappa coefficient. Based on mammography findings, 9 (36.4%) suspicious findings were observed in the lateral, 8 (30.8%) in the medial, and 5 (19.2%) in the interior of the breast. These results were confirmed in the CDP findings. Based on the pathology findings, 7 cases of lesions were of invasive type (4 IDC and 3 ILC), while the frozen results were free in all cases. The degree of concordance and correlation between mammography and CDP findings was 96.2%. Mammography findings were almost completely consistent with intraoperative CDP findings. Suppose there are suspicious findings in the mammography of patients who are candidates for conservative breast surgery. In that case, CDP can be used intraoperatively for these slight distortions of the surrounding tumor tissue to reduce recurrence and cost and increase patient survival.