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Unraveling heterogeneity in LUAD via multi-omics integration: molecular classification and therapeutic implications.
Shijian Zhen, Xiuying Zhang, Qunying Li, Zhihuan Liu, Dongdong Wang, Shuxue Xi, Shufang Shi, Geng Tian, Jialiang Yang, Haiwen Zhao, Jinyang Liu
Published: 202610.1007/s12672-026-04498-z
Abstract
Lung adenocarcinoma (LUAD) displays significant morphological and molecular heterogeneity both within and between tumors. This heterogeneity, coupled with the complexities of the tumor microenvironment (TME), notably influences LUAD progression and p…
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