Discover oncology
miR-4787-3p and miR-581 as predictive biomarkers for fibrosis and prognosis in pancreatic cancer.
Peng Chen, Meng Pan, Guanglong Hu, Zhengchao Shen, Xiaolong Zeng, Yuanxiang Zhang, Zhiyuan Chen, Chao Zhang, Xiaoming Wang
Published: 202610.1007/s12672-026-04389-3
Abstract
BACKGROUND: Pancreatic cancer (PC) is characterized by a profoundly immunosuppressive and fibrotic tumor microenvironment, driven largely by cancer-associated fibroblasts (CAFs). While microRNAs (miRNAs) are key regulators in PC, their specific roles…
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