Discover oncology
Phosphoproteome landscape of ARID1A and its implications in DNA damage response and breast cancer pathogenesis.
Apoorva Pai Kalasa Anil Kumar, Leona Dcunha, Althaf Mahin, Prathik Basthikoppa Shivamurthy, Suhail Subair, Athira Perunelly Gopalakrishnan, Athira C Rajeev, Rajesh Raju
Published: 202610.1007/s12672-025-03408-z
Abstract
ARID1A, a subunit of the SWI/SNF chromatin-remodeling complex, plays a critical role in maintaining genomic stability and regulating estrogen receptor (ER) signaling, yet its phosphorylation dynamics in cancer remain underexplored. This study employe…
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