Archives of pharmacal researchNF-E2-Related Factor 2Kelch-Like ECH-Associated Protein 1Extracellular MatrixOsteoarthritisCatechols
Cartilage extracellular matrix regeneration with 10-gingerol via KEAP1-NRF2-ARE axis for osteoarthritis therapy.
Yibo Ma, Chenhao Sun, Zongyue Wang, Changjian Chen
Published: 202510.1007/s12272-025-01579-5
Abstract
Osteoarthritis (OA) is characterized by oxidative stress, inflammation, and apoptosis, leading to an imbalance between cartilage extracellular matrix (ECM) synthesis and degradation. Gingerols can regulate multiple biological activities, indicating t…
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