Neuroscience bulletin
Oligodendroglial Mutant Huntingtin Contributes to Neuroinflammation in Huntington's Disease Mice.
Xinhui Li, Gongke Zhou, Shuying Xu, Tianqi Yang, Shurui Yin, Sitong Yang, Yi Wu, Xinqi Zhou, Su Yang, Huichun Tong, Xiao-Jiang Li, Shihua Li
Published: 202610.1007/s12264-025-01565-3
Abstract
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by poly-glutamine expansion in the mutant huntingtin (mHTT) protein. While the pathogenesis involves both cell-autonomous and non-cell-autonomous mechanisms, the role of spec…
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