International journal of hematology
Association of busulfan area under the curve with the development of neurotoxicity in children and adolescents receiving busulfan-containing conditioning regimens for stem cell transplantation.
Kenji Kishimoto, Sayaka Hyodo, Keizo Fukushima, Kei Irie, Shogo Horikawa, Suguru Uemura, Aiko Kozaki, Atsuro Saito, Toshiaki Ishida, Takeshi Mori, Daiichiro Hasegawa, Shoji Fukushima, Yoshiyuki Kosaka
Published: 202610.1007/s12185-026-04159-5
Abstract
Although several studies suggest that higher busulfan exposure is associated with neurotoxicity, research on the relevance of pharmacokinetic parameters is limited. The aim of this study was to explore the impact of busulfan area under the concentrat…
Preview only. Read the full abstract at the source