Biomolecular NMR assignmentsHumansNuclear Magnetic ResonanceBiomolecularProtein MultimerizationATPase Inhibitory Protein
NMR assignments of the human homodimeric mitochondrial ATP synthase inhibitor IF1.
Julia Jerolamon, Nathan N Alder, Andrei T Alexandrescu
Published: 202510.1007/s12104-025-10257-y
Abstract
ATPase inhibitory factor 1 (IF1) is the only known endogenous, proteinaceous inhibitor of mitochondrial ATP synthase in mammals. The inhibitor forms an antiparallel coiled-coil, which binds ATP synthase through an N-terminal α-helix extension that is…
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