Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Single-cell and bulk transcriptome analysis reveals the impact of inflammatory microglia on prognosis and immunotherapy response in primary glioblastoma.
Ziadoon Alyaqoobi, Yin He, Xiaosheng Wang
Published: 202510.1007/s12094-025-04135-1
Abstract
BACKGROUND: Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis. Microglia are key immune cells in the GBM tumor microenvironment (TME), yet their subtype-specific impact, particularly inflammatory microglia, remains poorly…
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