Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Beyond ALK fusion positivity: structural complexity as a prognostic indicator in first-line ALK-TKI therapy.
Dujiang Liu, Kaibo Ding, Linjing Zhou, Xinyue Li, Yanjun Xu
Published: 202510.1007/s12094-025-04085-8
Abstract
BACKGROUND: Although tyrosine kinase inhibitors (TKIs) have significantly improved survival outcomes in patients with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC), the efficacy of current TKIs for emerging ALK rearra…
Preview only. Read the full abstract at the source