Molecular neurobiologyAnimalsExonsEpilepsyHumansOligodendroglia
Transcript Imbalance from TENM4 Exon Skipping: Effects on Epilepsy and Genetic Pleiotropy.
Yasuyo Suzuki, Daniela Tiaki Uehara, Yasushi Enokido, Taeko Kawai, Noriko Nomura, Kenichiro Yamada, Jun-Ichi Takanashi, Hiroaki Miyahara, Johji Inazawa, Shin Hayashi
Published: 202510.1007/s12035-025-05559-0
Abstract
TENM4 is a transmembrane protein belonging to the teneurin family. It is localized in neurons and oligodendrocytes, where it regulates oligodendrocyte maturation and myelination. While missense variants of TENM4 were reported to cause essential tremo…
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