Molecular neurobiologyCaenorhabditis elegansAnimalsAmyloid beta-PeptidesCaenorhabditis elegans ProteinsUp-Regulation
Caenorhabditis Elegans Ortholog of TNF Alpha-Induced Protein 1 is Upregulated by TOL-1 and Exacerbates Amyloid-Beta-Associated Pathology.
Yanmei Su, Donghua Zhang, Yixin Li, Huan Gu, Wenhu Li, Wenhui Zhou, Ninghui Zhao, Xiaowei Huang
Published: 202510.1007/s12035-025-05554-5
Abstract
Neuroinflammation has been recognized as a central pathological mechanism in Alzheimer's disease (AD), modulated by diverse molecular pathways. Among these, the tumor necrosis factor superfamily (TNFSF) pathway serves as a pivotal mediator of inflamm…
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