Molecular neurobiologyAnimalsBrain InjuriesTraumaticBlood-Brain BarrierFatty Acid-Binding Proteins
Fatty Acid-binding Protein 4 Exacerbates Blood-brain Barrier Disruption Through the JNK/c-Jun/MMP12 Pathway After Traumatic Brain Injury.
Botao Ma, Dezhen Yang, Mengwu Tian, Shimei Dai, Zhuang Jing, Xuerui He, Xiaoqing Bao, Yinbo Long, Yu Gong, Yanling Dong, Jiaming Li, Gengshen Zhang, Hongbo Cheng, Jiegang Yu, Xiaoliang Wang
Published: 202510.1007/s12035-025-05539-4
Abstract
Elevated circulating levels of fatty acid-binding protein 4 (FABP4) correlate with poor prognosis in brain injury patients. However, the molecular mechanisms by which FABP4 regulates blood-brain barrier (BBB) disruption after traumatic brain injury (…
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