Molecular neurobiologyHumansKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Signal TransductionOxidative Stress
Nrf2/Keap1 Signaling Axis in the Brain: Master Regulator of Oxidative Stress in Neurodegenerative and Psychiatric Disorders.
Falguni Goel, Payal Singh, Sachchida Nand Rai, Dharmendra Kumar Yadav
Published: 202510.1007/s12035-025-05517-w
Abstract
Oxidative stress is a crucial factor in the development of CNS disorders, including neurodegenerative and psychiatric conditions. The Nrf2/Keap1 signaling axis plays a central role in defending against oxidative damage by regulating antioxidant and c…
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