Molecular neurobiologyAnimalsSirtuin 1AutophagyApoptosisSignal Transduction
Resveratrol Attenuates H2O2-induced Aging and Apoptosis in Mouse Hippocampal Neuron HT22 Cells by Activating Autophagy via the SIRT1/FoxO1 Signaling Pathway.
Minghui Cai, Qi Guo, Jiaxin Li, Xiaoqi Dai, Huiyu Su, Wenwen Zhang, Na Qiang, Geng Li, Zihan Jin, Hui Zhu
Published: 202510.1007/s12035-025-05489-x
Abstract
The factors influencing hippocampal aging are complex, and it remains challenging to identify effective anti-aging drugs and reveal pharmacological mechanisms. This study investigates the effects of autophagy mediated by the SIRT1/FoxO1 signaling pat…
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