Molecular neurobiologyAnimalsCatechinNeurogenesisHippocampusToll-Like Receptor 4
Epigallocatechin-3-gallate Restores X-irradiation-Induced Impairments in Cognitive Function and Hippocampal Neurogenesis by Suppressing the TLR4-NOX3/4 and ROS-NF-κB Pathways in Microglia.
Kyung-Joo Seong, Sang-Won Lee, Jin Ho Lee, Hyun-Mi Ko, Taek-Keun Nam, Tae-Young Kim, Won-Seok Choi, Ji-Yeon Jung, Won-Jae Kim
Published: 202510.1007/s12035-025-05473-5
Abstract
X-irradiation, commonly used to ablate tumor cells, disrupts hippocampal neurogenesis and neurobehavioral function. However, strategies to restore X-irradiation-induced impairments in hippocampal neurogenesis and cognitive function are not well estab…
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