Molecular neurobiologyAnimalsAlzheimer DiseaseOxidative StressMitochondriaAmyloid beta-Peptides
PSMD4 Alleviates Aβ₁₋₄₂-Induced Mitochondrial Dysfunction and Oxidative Stress via the PGC-1α/Nrf Axis in Alzheimer's Disease Models.
Min Yuan, Xiao-Jian Han, Chao-Qun Luo, Hai-Li Pan, Huang-Yan Zhou
Published: 202510.1007/s12035-025-05445-9
Abstract
This study aimed to investigate the role of 26S proteasome non-ATPase regulatory subunit 4 (PSMD4) in regulating mitochondrial function and oxidative stress in Alzheimer's disease (AD) and to explore its potential molecular mechanism in Aβ-induced ne…
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