Molecular neurobiologyGastrointestinal MicrobiomeHumansStrokeMendelian Randomization AnalysisTumor Necrosis Factor Receptor Superfamily
Mendelian Randomization Unlocks Stroke Therapeutics: Dioscin Inhibits CD27-Driven Neuroinflammation via Gut Microbiota Modulation.
Haozhou Tan, Shengli Li, Han Yan, Fangfang Li, Yang Yao, Ying Li, Qian Feng
Published: 202510.1007/s12035-025-05439-7
Abstract
Research on the gut-brain-immune axis shows it plays a critical role in ischemic stroke, but the exact causal links between gut bacteria imbalance, immune system problems, and brain blood vessel damage remain unclear. To investigate this, we combined…
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