Molecular neurobiologyHumansAnimalsRepressor ProteinsNeurodegenerative DiseasesNeurons
The Dynamic Roles of Repressor Element 1-Silencing Transcription Factor (REST): A Double-Edged Sword in Neural Health and Disease.
Taslima Akter Eva, Avinash Shenoy, Veer B Gupta, Viswanthram Palanivel, Akanksha Salkar, Sohrab Nowroozi Nasab, Nitin Chitranshi, Mehdi Mirzaei, Yuyi You, Stuart L Graham, Devaraj Basavarajappa, Vivek Gupta
Published: 202510.1007/s12035-025-05304-7
Abstract
The repressor element 1-silencing transcription factor (REST), or neuron-restrictive silencer factor (NRSF), is crucial for gene regulation since it binds to chromatin and recruits chromatin-modifying enzymes. Acting as a regulatory hub, REST orchest…
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