Molecular biotechnology
Transcriptome Analysis of Differentially Expressed Genes and Molecular Pathways Involved During Osteoclast Differentiation.
Lei Zhang, Jingjing Wu, Ni Zhou, Shuting Yang, Jiangjie Chen, Chenghao Xu, Shaohua Fan, Weixing Huang, Xiaofang Ying, Liwei Zhang
Published: 202510.1007/s12033-025-01540-3
Abstract
Bone remodeling relies on balanced osteoclast and osteoblast activity, with dysregulated osteoclast differentiation contributing to pathologies like osteoporosis. While RANKL/M-CSF signaling and master regulators (NFATc1, c-Fos) are established, comp…
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