Journal of molecular neuroscience : MNAnimalsAmyotrophic Lateral SclerosisMiceTransgenicMale
Retrospective Study of the Physiological and Molecular Features of the S-FUS (1-359) Mouse Transgenic Model with an ALS-like Phenotype: Lifespan, Body Weight Dynamics, Movement Disorders, and Dysregulation of the Dopaminergic System.
Evgeny Bronovitsky, Kirill Chaprov, Anastasia Khizeva, Tamara Ivanova, Ekaterina Pravdivceva, Timofey Bobkov, Olga Morozova, Anastasia Krayushkina, Vladimir Nebogatikov, Natalia Ninkina, Aleksey Ustyugov
Published: 202610.1007/s12031-025-02450-4
Abstract
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease leading to disability and death. Genetic animal models, like transgenic mice, are critical for studying disease mechanisms and developing therapies. Model validity, experimental…
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