Journal of molecular neuroscience : MNHumansMolecular Docking SimulationSphingosine-1-Phosphate ReceptorsMolecular Dynamics SimulationMultiple Sclerosis
Irilone and Lupinisoflavone C as Potential Plant-Based Modulators of S1PR1 for Neuroimmune Modulation in Multiple Sclerosis: Insights from Molecular Docking and Dynamics.
Taghreed A Majrashi, Abdulrhman Alsayari, Mohammad Y Alshahrani, Mohammad Abohassan, Sourav Mohanto, Mohammad Zaki Ahmad, Shadma Wahab
Published: 202510.1007/s12031-025-02446-0
Abstract
The S1PR1 gene encodes the sphingosine-1-phosphate receptor 1, a member of the G protein-coupled receptor (GPCR) family that is highly expressed in endothelial cells. S1PR1 protein plays a pivotal role in regulating cell migration, maintaining vascul…
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