Neuromolecular medicineAnimalsZebrafishMorpholinosMitochondrial DiseasesGene Knockdown Techniques
Morpholino Knockdown in Zebrafish: A Tool to Investigate the Functional Impact of Variants of Unknown Significance in Mitochondrial Diseases.
Mateus Laranjeira, Jorge M A Oliveira, Filippo M Santorelli, Maria Marchese, Célia Nogueira
Published: 202510.1007/s12017-025-08890-w
Abstract
Mitochondrial diseases (MDs) are heterogeneous multisystemic disorders often caused by genetic defects in either nuclear or mitochondrial DNA. Although next-generation sequencing technologies have dramatically expanded the number of variants associat…
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