Frontiers of medicine
ILKAP drives hepatocellular carcinoma progression by modulating PGAM1-mediated glycolytic reprogramming.
Juejiashan Li, Yihong Chen, Qiyi Qian, Yating Gao, Nana Zhou, Xiaoyan Li, Qiuran Xu, Dongsheng Huang, Wenhu Chen
Published: 202510.1007/s11684-025-1178-7
Abstract
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, necessitating novel therapeutic targets. This study explores the oncogenic role of integrin-linked kinase-associated phosphatase (ILKAP) in HCC and its underlying mechanis…
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