Frontiers of medicine
Metabolic biomarkers for predicting onset and severity of CAR-T therapy-induced cytokine release syndrome in multiple myeloma.
Xiaolin Ma, Tuantuan Gui, Shuangshuang Yang, Shiwei Jin, Jing Qiao, Yinyin Xie, Junyu Wang, Wanyan Ouyang, Gaoxian Song, Xiao Yi, Chenglin Liu, Mengmeng Pan, Weiyang Liu, Niu Qiao, Yuting Dai
Published: 202510.1007/s11684-025-1176-9
Abstract
Chimeric antigen receptor T-cell (CAR-T) therapy has been successfully applied in clinical treatment, especially for hematologic malignancies such as multiple myeloma (MM), but its broad application is limited by cytokine release syndrome (CRS), a po…
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