In vitro cellular & developmental biology. Animal
Neuroprotective effect of Saikogenin F on corticosterone-induced cytotoxicity in PC12 cells involves P2X7R-NLRP3 and cAMP-PKA pathways.
Tong Cui, Meng Li, Shimeng Zhang, Wenxia Gong, Xuemei Qin, Guanhua Du, Yuzhi Zhou
Published: 202610.1007/s11626-025-01146-8
Abstract
Saikogenin F (SGF) is a metabolite of Saikosaponin A (SSA) in vivo. However, in comparison to SSA, the neuroprotective efficacy and mechanisms of SGF remain uncertain in depression. The objective of this study was to explore the neuroprotective effec…
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