Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyAnimalsGangliaSpinalHMGB1 ProteinNerve Regeneration
HMGB1-Induced Neurite Outgrowth in the Dorsal Root Ganglion Neurons and Regeneration Priming after their Axonal Injury by Sciatic Nerve Crush.
Fumiko Sekiguchi, Yui Nakatake, Akifumi Adachi, Maho Tsubota, Yasuko Tomono, Masahiro Nishibori, Atsufumi Kawabata
Published: 202510.1007/s11481-025-10261-y
Abstract
High mobility group box 1 (HMGB1), a nuclear protein, once released extracellularly, exists in two different active forms, i.e., all-thiol (at)- and disulfide (ds)-HMGB1. Given that HMGB1 promotes neuritogenesis, we examined whether at/ds-HMGB1 would…
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