Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyAnimalsFemaleZebrafishPyrimidinesAlzheimer Disease
Pyrimidine Derivative, (E)-N-[4-(4-Chlorophenyl)-6-(4-Methylphenyl)Pyrimidin-2-yl]-1-(Furan-2-yl)Methanimine, Named BN5 Ameliorates Cognitive Dysfunction and Regulates esr1 and esr2b Expression in Female In Vivo Zebrafish Alzheimer Model.
B Aswinanand, Kumar Nallasivan Palani, Sanjai Dharshan Santhanam, Karthikeyan Ramamurthy, Senthilkumar Palaniappan, M Valan Arasu, Ajay Guru, Muthumareeswaran Muthuramamoorthy, Kathiravan Muthu Kumaradoss, Jesu Arockiaraj
Published: 202510.1007/s11481-025-10248-9
Abstract
Alzheimer's disease (AD) is the most common form of dementia, characterized by a progressive decline in cognitive functions. It is more prevalent in women, especially after menopause, likely due to factors like longer life expectancy and hormonal cha…
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